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Syloid® FP Silica - Multifunctional Excipient for Pharmaceutical & Nutraceutical Formulations

 

Grace Syloid® FP Silica offers efficiency and performance in many pharmaceutical and nutraceutical applications, helping to solve powder flow and caking challenges. Manufactured in the USA, Syloid FP silica is engineered hydrated silicon dioxide produced under controlled conditions, meeting USP/NF, EMA, Health Canada, and ANVISA requirements and offering high chemical purity and performance.

Univar Solutions can support your pharmaceutical excipient needs through a global network of credentialed distribution centers across North America, Europe, and Latin America. Our dedicated pharma ingredients team has the technical expertise to help you navigate the research, development, and commercialization phases of your pharmaceutical or nutraceutical product journey.

 

Excipient products available:

GRADE UNIT SYLOID 63FP SYLOID 72FP SYLOID 244FP SYLOID XDP 3050 SYLOID XDP 3150
Particle size UM 6 6 6 50 150
Loss on drying (145C) % 5.0 max 5.0 max 5.0 max    
Loss on ignition (1000C) % 8.5 max 8.5 max 8.5 max    
Oil absorption g/100g 90 220 300 300 300
Surface area M2/gm 700 350 300    
pH (5% H2O Slurry)   4.7 6.7 7    
Bulk density Lb/ft3 29 10 6.2 17  
SiO2 content % 99.6 99.6 99.6 99.6 99.6
Meets USP/NF   YES YES YES YES YES


Syloid(R) FP Silica characteristics:

  • Meets USP/NF Monograph
  • Formed using a gelation process; washed, sized, and dried to a fine dry powder
  • Resilient structure resistant to grind
  • High density, lower dusting
  • High porosity for enhanced adsorptive capacity
  • Pores integral to the structure
  • Narrow pore structure
  • Easy to incorporate actives, providing more uniform dispersion of actives and improved content uniformity

 

 

 

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Industries and applications

 

 

Glidant:

  • Forms layer around bulk powder, ball bearing affect
  • Helps achieve improved powder flow and minimize sticking and agglomeration
  • Improves compression rates and consistency of compression
  • Increases active uniformity

 

Active Carrying:

  • High porosity/oil absorption increases absorptive capacity for oils and water
  • Liquid ingredients can be converted into free-flowing powders
  • Increased advantages for high doses of API in oral suspensions and tablets

Tabletting:

  • Consistent compression
  • Improved hardness/structural stability
  • Enhanced coating
  • Improved dissolution

 

Lotions:

  • Viscosity modifiers for topicals and semi-solids with load levels up to 25%
  • Matting agent
  • Improves and protects powder from agglomeration
  • Exfoliation
  • Fragrance and active carrying

Choose the right Syloid® FP Silica for your application

GRADE SYLOID 63FP SYLOID 72FP SYLOID 244FP SYLOID 244 SYLOID XDP 3050 SYLOID XDP 3150
Free flow *** **** ***** ***** **** ****
Anti-caking * *** ***** ***** **** ****
Tabletting * ** ****** ***** ***** *****
Shelf-life stability ***** ** ** * ** **
Dust *** *** *** *** ***** *****